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approximately 40% of patients symptoms can last longer than   1.3   Smoking is a chronic relapsing disease
          3-4 weeks. 12
          Nicotine withdrawal symptoms represent the sum of all changes
          induced by abrupt cessation of nicotine consumption, which is   1.3.1 Relapse patterns
          particularly difficult in the first two to six weeks and which must be   Nicotine/tobacco  dependence  is a  chronic relapsing  condition,
          accompanied by qualified medical assistance and psychological   which is mostly acquired during adolescence.5 Tobacco
          support. Thus the best strategy recommended by all smoking   dependence has many characteristics of a chronic disease
          cessation guidelines for treating nicotine dependence is to   with most smokers persist in consuming tobacco for years or
          combine pharmacological treatment with psycho-behavioural   decades.
          therapy. 13                                      “Relapse” is considered a return to regular smoking by someone
                                                           who has quit. Relapse typically refers to a period of several days
          Smoking status                                   or more of continuous smoking after a period of abstinence.
          It is recommended that all clinicians appropriately assess of   “Failures” or “relapses” mean daily smoking for at least three
          current and past tobacco use with patients.      days after a period of at least 24 hours without any smoking.
          The following definitions are used for the classification of   A “lapse” or a  “slip” denotes the use of tobacco after a prior
          smoking status:                                  period of abstinence that does not result in the return to regular
           •  Non-smoker is a person who has not smoked more than 100   smoking. This may be the case of quitters and ex-smokers who
            cigarettes in his/her life-time (or 100 g of tobacco, in the case   smoke less than one cigarette per day in up to three days in one
            of pipes, cigars or other tobacco products).   week, or smoke any number of cigarettes one day in one week in
           •  Daily smoker is a person who has smoked on a daily basis   the week before any scheduled visit. A lapse may be an isolated
            for at least three months.                     event that is followed by a renewal of abstinence, or it is a strong
           •  Occasional smoker is a person who has smoked, but not on   predictor of relapse.
            a daily basis.                                 Among ex-smokers relapse is common. Relapse most
           •  Ex-smoker is a person who has quit smoking for at least six   frequently occurs within the first few days of a quit attempt when
            months.                                        withdrawal symptoms are the greatest.  Over 75% of unaided
                                                           quitters relapse within the first week making this a critical period
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          Some standard questions considered helpful in assessing   of time.  Figure 1.2 depicts the likelihood of relapse within the
          smoking status are as follows:                   first year of quitting.
           1. Have you ever smoked cigarettes or used other tobacco   Once patients are smoke free for two to three months their risk
            products (e.g. pipes, cigars etc.)?            of relapse is much lower – but by no means gone.  Even among
           For current smokers:                            tobacco users who may have succeeded in quitting for brief or
           2. How many cigarettes (or other tobacco products, e.g. pipes,   longer periods of time the risk of relapse remains high. Patients
            cigars etc.) do you usually smoke per day?     who stay smoke free for at least 12-months have a 35% lifetime
           3. How many years have you been smoking?        probability of relapse (See Figure 1.3). 14
           4. How many  cigarettes  have  you smoked  in  your life?  Is it
            more or less than 100?                         1.3.2 Treatment of tobacco dependence after cessation
           5. Do you smoke every day/on certain days/in specific   Tobacco dependence may need persistent and repeated
            situations? Which situations?                  therapeutic interventions, as well as long- term follow-up until
           For ex-smokers:                                 it is cured. 15
           6. How many years/months has it been since you quit smoking?   Understanding its chronic nature implies long-term observation,

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